目的:分析慢性泪囊炎患者的优势菌变迁及对抗生素的敏感性。方法:对40例慢性泪囊炎患者的泪囊分泌物取样,进行细菌培养、分离、鉴定及药物敏感实验。结果:40例慢性泪囊炎患者泪囊分泌物培养,39例为阳性,共分离出50株阳性菌。G+球菌27株(54%),其中表皮葡萄球菌22株(44%),G-杆菌为14株(28%)。表皮葡萄球菌对利福平的敏感率为91%,左氧氟沙星66%,氧氟沙星60%。结论:G+球菌为引起慢性泪囊炎的主要菌,其中表皮葡萄球菌为优势菌,应重视老药新用及一线药物耐药性的变迁,结合药敏结果合理选用抗生素。

AIM:To analyze the predominant bacteria changes in patients with chronic dacryocystitis and antibiotic sensitivity.·METHODS:Material of lacrimal secretion in 40 cases of patients with chronic dacryocystitis was sampled for bacterial culture,isolation,identification and drug sensitivity test.·RESULTS:Of the 40 cases of chronic dacryocystitis patients with lacrimal secretion culture,39 cases were positive,a total of 50 strains positive bacteria were isolated.There were 27 strains of G+ cocci (54%) with 22 strains of Staphylococcus epidermidis (44%) and G-bacilli 14 strains(28%).Staphylococcus epidermidis sensitive to rifampin was 91%,levofloxacin 66% and ofloxacin 60%.·CONCLUSION:G+ cocci is the main bacteria of chronic dacryocystitis including Staphylococcus epidermidis as the predominant bacteria.We should pay attention to the new uses of old drugs,and changes in first-line drug resistance,combination with drug sensitivity results for reasonable selection of antibiotics.

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