目的：评价甲基纤维素和透明质酸钠制作软壳技术在白内障超声乳化手术中的效果。 方法：Ⅲ级核以上白内障患者76例82眼。随机分为研究组（联合使用甲基纤维素和透明质酸钠）41眼、对照组（Duo Visc）41眼，两组手术时前房使用不同材料注射。 结果：研究组和对照组术后第1d平均裸眼视力分别为050±0.22,0.51±0.27，研究组与对照组之间无显著差异，术后7d平均裸眼视力分别为0.61±0.17,0.63±0.18，术后第1d平均内皮细胞丢失率研究组和对照组分别为7.1%,6.9%，差异无统计学意义。结论：甲基纤维素和透明质酸钠制作软壳技术能达到进口材料同等的保护角膜内皮效果和安全性。

AIM: To evaluate the efficacy of soft shell technique with Sodium Tvlose and sodium hyaluronate during cataract phacoemulsification with intraocular lens(IOL) implantation. METHODS: Eighty two eyes of 76 patients with mature cataract underwent phacoemulsification with IOL implantation, including 41 eyes using the soft shell technique with Sodium Tvlose and sodium hyaluronate(study group). RESULTS:The average naked vision was 0.50±0.22, 0 51±0.27 respectively the first day after operation, the difference between the study group and control group was not statistically significant, The average naked vision was 0.61±0.17, 0.63±0.18 respectively seven days after operation, there was no statistically significant difference between the two groups. The loss rate of corneal endothelial cells 1 month after surgery was 7.1% in the study group, 6.9% in the control group. There was no statistically significant difference between the two groups. CONCLUSION: The soft shell technique with Sodium Tvlose and sodium hyaluronate is the same safe and effective in protecting corneal endothelial cells during cataract surgery in patients with mature cataract as the import material.

R779.66