目的:比较白内障超声乳化联合植入Acrysof ResToR及Acrysof Natural的临床效果。方法:随机化临床试验,选择年龄性白内障患者,ReSTOR组30例36眼,植入ReSTOR SA60D3衍射型多焦点人工晶状体(MIOL),Natural组28例30眼,植入NaturalSN60AT单焦点人工晶状体(SIOL)。观察术后未矫正远视力(UCDVA)、未矫正近视力(UCNVA)、最佳矫正远视力(BCDVA)、最佳矫正近视力(BCNVA)、远矫正下的近视力(DCNVA)。中间距离视力(40,60,80cm)和视觉症状。结果:两组患者UCDVA,BCDVA和BCNVA无显著差异,术后ReSTOR组UCNVA,DCNVA及中间距离视力明显优于Natural组(P<0.05)。ReSTOR组术后4wk UCNVA,UCDVA明显优于1wk。术后12wk,ReSTOR组术后UCNVA优于中间距离视力(40cm),差异有统计学意义。而中间距离视力之间(40与60cm;60与80cm)无统计学差异。ReSTOR组患者术后受眩光和光晕影响较Natural组明显(P<0.05),但均可忍受。ReSTOR组戴镜率低于Natural组,差异有统计学意义(P<0.05)。结论:新型衍射型MIOL ReSTOR能提供良好的全程视力,有效减低患者对老视镜的依赖,提高白内障患者术后的视觉质量。

·AIM:To compare the clinical effects of Acrysof ReSTOR multifocal intraocular lens(IOL)and the monofocal Acrysof Natural IOL implantation after phacoemulsification.·METHODS:Random clinical trial of 58 patients 66 eyes with age-related cataract were divided into two groups:ReSTOR group included 30 patients 36 eyes implanted with ReSTOR SA60D3 multifocal IOL(MIOL),and Natural group included 28 patients 30 eyes implanted with Natural SN60AT monofocal IOL.Measurements were taken after operation,including uncorrected distant visual acuity(UCDVA),uncorrected near visual acuity(UCNVA),best corrected distant visual acuity(BCDVA),best-corrected near visual acuity(BCNVA),distant corrected near visual acuity(DCNVA),intermediate vision(40,60,80cm)and visual symptoms.·RESULTS:There was no significant difference in UCDVA,BCDVA,BCNVA between 2 groups.UCNVA,DCNVA and intermediate vision(40,60,80cm)were significantly higher in the ReSTOR group(P<0.05).In ReSTOR group the UCDVA、UCNVA at 4 weeks were significantly better than that of 1 week.At the 12 weeks postoperatively,UCNVA was significantly better than intermediate vision(40cm)in ReSTOR group and no statistical difference was noted between the intermediate vision(40 vs 60cm,60 vs 80cm).Adverse symptoms such as glare and haloes were significantly more obvious in ReSTOR group than in Natural group(P<0.05).The rate of dependence on glasses in the ReSTOR group was significantly lower than that of Natural group(P<0.05).·CONCLUSION:Acrysof ReSTOR multifocal IOL provide excellent full range of vision,effectively decrease the dependence of glasses,improve the visual quality after surgery.·

R779.66

中国广西壮族自治区研究生创新资助项目(No.2008105981002M182)~~