目的:探讨角膜波面像差引导的准分子激光个体化屈光手术(optimized refractive keratectomy-customized ablation,ORK)治疗高度近视患者术后角膜表面规则性和对称性情况。方法:对50例100眼高度近视患者行角膜波面像差引导的准分子激光个体化屈光手术治疗,对同期50例100眼高度近视患者用传统LASIK治疗,观察两组疗效,并采用角膜地形图检查仪测量两组术后6mo的角膜地形图变化[包括角膜曲率,K1,K2,表面非对称指数(surface asym-metry index,SAI),表面规则指数(surface regularity index,SRI)]。结果:与术前比较,两组术后角膜曲率、K1,K2,SAI,SRI降低(均为P<0.05)。ORK组术后6mo SAI,SRI改善优于传统组(均为P<0.05)。结论:角膜波面像差引导的准分子激光个体化屈光手术与传统LASIK比较,角膜波面像差引导的准分子激光个体化屈光手术治疗的患者术后6mo角膜规则性和对称性优于应用传统LASIK治疗的患者。

·AIM:To investigate the corneal surface regularity and symmetry after optimized refractive keratectomy-customized ablation(ORK)surgery for treatment of high myopia.·METHODS:Fifty patients 100 eyes with high myopia underwent optimized refractive keratectomy-customized ablation therapy,and for the same period 50 patients 100 eyes with high myopia were treated with conventional LASIK,the effect of two groups was observed,and the corneal topography changes,including corneal curvature,K1,K2,surface asymmetry index(SAI),surface regularity index(SRI)of the two groups after 6 months were observed with corneal topography.·RESULTS:Compared with that of preoperative,postoperative corneal curvature,K1,K2,decreased,SAI,SRI reduced(each P <0.05).The improvement of was SAI and SRI in ORK group after 6 months superior to that in the LASIK group(each P<0.05).·CONCLUSION:The cornea of the patients who underwent optimized refractive keratectomy-customized ablation therapy is more of regularity and symmetry than that of conventional LASIK patients after 6 months.·

R779.63