[关键词]
[摘要]
视网膜和脉络膜新生血管可引发玻璃体出血、视网膜下出血、牵引性视网膜脱离等,从而危害患眼视力。这类病变常见于老年性黄斑变性(age related macular degeneration,AMD)、糖尿病视网膜病变(diabetic retinopathy,DR)、视网膜静脉阻塞(retinal vein occlusions,RVO)、早产儿视网膜病变(retinopathy of prematurity,ROP)等眼底病。当前,药物治疗新生血管(neovscularization,NV)主要是针对NV生成的不同阶段抑制其生长。本文综述了目前已用于临床及正在进行临床试验的治疗眼底新生血管的药物。
[Key word]
[Abstract]
·Retina and choroid neovascularization(NV)may induce vitreous hemorrhage,subretinal hemorrhage and tractional retinal detachment and usually result in poor vision.It is often seen in the eyes with age-related macular degeneration(AMD),diabetic retinopathy(DR),retinal vein occlusions(RVO)and retinopathy of prematurity(ROP).At present,drugs of NV mainly target the different phases of the angiogenesis and suppress its growth.We discusse the present anti-neovascular drugs which are used on clinic or under the clinicaltrial.·
[中图分类号]
R774.5
[基金项目]
中国上海市科委基础重点资助项目(No.08JC1415600);中国上海市重点学科建设资助项目(No.S30205)~~
