随着锰在影像学和实验研究中的不断应用,其毒性损伤已经成为近期人们研究的热点。大量研究证明,锰作为机体微量元素,堆积后的损伤主要表现于神经系统。我们从锰作为影像增强剂这一角度对其给药方式、机体损伤和损伤机制的研究做一综述。

·As the manganese has been applied continually in the imaging studies and experimental researches,its toxic injury has been a hotspot.Many studies have demon-strated that the damage of large accumulation of mangan-ese,as a body trace element,is expressed mainly in the nervous system.This article will summarize the papers concerned with the delivery method,body injury and neurotoxic mechanism of manganese,while man-ganese was applied as an image intensifier.·

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