目的:观察卵磷脂络合碘与复方血栓通胶囊在治疗不同病程玻璃体混浊时的疗效及其对比。方法:发病时间不等的玻璃体混浊患者随机分配接受卵磷脂络合碘或复方血栓通胶囊治疗。治疗前及治疗30,60d后分别行裂隙灯、眼底镜等检查,观察玻璃体混浊情况和视力变化,并评定混浊等级。结果:治疗30d后,新发组和短期组血栓通胶囊治疗有效率均显著低于卵磷脂络合碘治疗组(P<0.05);治疗60d后,陈旧组经血栓通治疗有效率显著高于卵磷脂络合碘治疗组(P<0.05),且各组总有效率均显著高于治疗30d的有效率(P<0.05)。长期组、陈旧组与新发组相比,经两种药物治疗后的总有效率均明显降低(P<0.01)。结论:卵磷脂络合碘对发病时间较短的玻璃体混浊治疗效果优于复方血栓通胶囊,而复方血栓通胶囊治疗慢性陈旧性玻璃体混浊效果理想。对玻璃体混浊一经诊断尽早施治,并适当延长治疗时间,有助于提高治疗效果。

·AIM:To evaluate the clinical effect of lecithin-bound iodine and fufangxueshuantong capsule in the treatment of vitreous opacities.·METHODS:Vitreous opacity patients which had different disease time were randomly divided into two groups,the lecithin-bound iodine(LBI)group and the fufangxue-shuantong capsule group.The vitreous body turbidity situation,change of eyesight were observed under the direct ophthalmoscope and slit-lamp before the treatment and 30 days,60 days after oral drug treatment.At the same time,the vitreous body turbidity grade was evaluated.·RESULTS:After 30 days’ treatment,the effective rate of fufangxueshuantong was significantly lower than that of LBI in the fresh and short-term groups(P<0.05).After 60 days’ treatment,in the old group,there was a much higher effective rate in patients who had taken fufangxueshuantong than those who had taken LBI(P<0.05).Moreover,the total effective rate in each group were significantly higher than the efficiency of the 30 days’ treatment(P<0.05).Compared with the fresh group,the total effective rates of the long-term group and old group were significantly decreased after two drugs’ treatment(P<0.01).·CONCLUSION:LBI is more effective to the fresh and short-term vitreous opacities than fufangxueshuantong capsule,and fufangxueshuantong capsule is an ideal treatment for chronic old vitreous opacities.To extend the treatment time of vitreous opacities and offer early treatment will contribute to the improvement of treatment effectiveness.·

R776.4