目的:探讨用深低温保存的角膜材料行板层角膜移植术治疗边缘性角膜变性的效果。方法:对角膜边缘已经很薄,接近穿孔或已经穿孔的27例边缘性角膜变性患者,用深低温保存的角膜材料行板层角膜移植术治疗,观察术后视力,眼压,植片愈合及并发症等情况,随访时间为2a。结果:术后角膜边缘病变均未发展,术后1wk视力基本与术前相同,1.0者11例,0.6～0.8者6例,0.3～0.5者8例,0.05～0.25者2例。原穿孔的病例有术后一过性高眼压、前房反应、瞳孔欠圆等并发症。2a内只有3例发生了术后排斥反应。结论:用深低温保存的角膜材料完全可以用来进行板层角膜移植治疗边缘性角膜变性,弥补了新鲜角膜的来源限制与时效限制,是治疗边缘性角膜变性的理想材料。

AIM:To investigate the effect of lamellar keratoplasty with long-term cryopreserved corneal materials for the treatment of Terrien’s marginal corneal degeneration.·METHODS: Twenty-seven patients with thin edges of the corneas which were almost perforated or already perforated underwent the lamellar keratoplasty with long-term cryopreserved corneal materials. The postoperative visual acuity, intraocular pressure, the graft healing and the complications were observed. The period of follow-up was 2 years.·RESULTS: The marginal corneal lesions were not developed postoperatively. The postoperative visual acuities after 1 week were almost the same as that of preoperative, 1.0 in 11 cases, 0.6 to 0.8 in 6 cases, 0.3 to 0.5 in 8 cases, 0.05 to 0.25 in 2 cases. The complications such as transient high intraocular pressure, anterior chamber reaction, the not round pupil could be found in patients with preoperative corneal perforation. The postoperative graft rejection occurred in only 3 cases in 2 years.·CONCLUSION: The long-term cryopreserved corneal materials can be used for lamellar keratoplasty for the treatment of Terrien’s marginal corneal degeneration. Being the alternatives of fresh corneas, without source restriction and timing limitation, they are the ideal materials for the treatment of Terrien’s marginal corneal degeneration.

R779.65