目的:观察手术干预对真菌性角膜溃疡预后的影响,探讨手术治疗对角膜溃疡的意义。方法:对39例39眼真菌性角膜溃疡分别采用单纯病灶清除、病灶清除联合羊膜移植、病灶清除联合结膜瓣遮盖等手术治疗,并给予规范化药物治疗。随访>6mo观察治疗效果及预后。结果:其中34眼一次手术后角膜感染得到有效控制;2眼术后1wk内接受二次手术角膜感染得到控制;3眼角膜穿孔继发眼内炎行眼球内容摘除术。结论:手术治疗对有效控制真菌性角膜溃疡有重要意义,根据病情采用适当的手术干预对挽救患者眼球解剖及功能完整性有重要价值。

AIM:To investigate the influence of surgery interven-tion on the prognosis of fungal corneal ulcer,and to discuss the importance of surgery for the treatment of serious corneal ulcer. ·METHODS:Altogether 39 patients with fungal corneal ulcer underwent focus of infection cleaning,focus of infection cleaning with amniotic membrane grafting or focus of infection cleaning with conjunctival flap covering surgery separately,followed with standard medical treatment. The outcome of the treatment was recorded and evaluated through follow-up visit of more than six months. ·RESULTS:Thirty-four patients were cured through one time surgery,two patients were cured through two time surgery,while the other three eyeballs were eviscerated due to corneal perforation and secondary endophthal-mitis. ·CONCLUSION:Surgery may play an important role in the rescue of the anatomy and function of eyeballs infected with fungus.

R779.6