目的:探讨黏弹剂在复合小梁切除术中的应用。方法:病例对照研究。选择原发性青光眼需接受复合小梁切除术的患者56眼,随机数字法分为两组,每组28眼,观察组术中均使用黏弹剂,对照组均未在术中使用黏弹剂。观察两组患者术后前房、滤过泡、眼压、角膜内皮的变化并作对比。结果:观察组术后早期均能较好的形成前房,术后3mo观察组的滤过泡更为弥散隆起,功能型滤过泡(96%),对照组滤过泡相对扁平,功能型滤过泡(93%);术后早期观察组眼压较对照组稍偏高,术后3mo观察组眼压较对照组更低一些;两组术前术后角膜内皮细胞情况无统计学差异。结论:在复合小梁切除术中使用黏弹剂可使术后早期前房更稳定,并能支撑滤过道顺利渡过早期的瘢痕化期,从而提高手术的成功率。

AIM:To explore the effects of sodium hyalurantae in complex trabeculectomy. ·METHODS:Case-control studies. 56 eyes with primary glaucoma who need complex trabeculectomy were randomly divided into observation group and control group with 28 eyes in each group. Patients in the observation group were applied the sodium hyalurantae,and the control group were not applied during the operation. The changes in anterior chamber,bleb,IOP and corneal endothelial cells in two groups were observed. ·RESULTS:The anterior chambers of 28 eyes in observation group formed early postoperatively. The shapes of filter blebs in observation group were better than control group at three months after operation. Functional filtering bleb appeared in 27 eyes(96%) in observation group and functional filtering bleb appeared in 26 eyes (93%) in control group. IOP of observation group is slightly higher than that of control group early postoperatively,and three months after operation,IOP of observation group was somewhat lower than that of control group. There was no statistical difference between the corneal endothelial cells of preoperation and postoperation in two groups. ·CONCLUSION:It can make the anterior chamber form better by using sodium hyalurantae in complex trabeculectomy,and it can support filtration path to inhibit scar formation and increase the successful rate of complex trabeculectomy.

R779.6