目的:探讨波前像差引导的个体化切削技术对LASEK患者术后高阶像差的影响。方法:将均方根(RMS)值>0.3的不适合做LASIK术的近视患者40例80眼随机分为2组。其中1组20例40眼行普通LASEK术,另1组20例40眼应用波前像差引导的个体化切削程序(Zyoptix)进行LASEK术;所有术眼术前及术后1,3mo行像差测量。结果:术前两组高阶像差,彗差,球差相比无统计学意义(P>0.05),在6mm的瞳孔直径下,术后1mo两组高阶像差,彗差,球差较术前增加,个体化切削组高阶像差,彗差,球差增加幅度低于常规组,有统计学意义(P<0.05),术后3mo时,总体高阶像差,彗差,球差较1mo时有所下降,个体化组增加幅度仍小于普通组。结论:Zyoptix波前引导LASEK术后高阶像差增加幅度小于普通LASEK术。

·AIM:To investigate the influences of wavefront guided techniques on the higher-order aberrations after laser-assisted subepithelial keratectomy(LASEK)surgery.·METHODS:Totally 40 patients 80 eyes,whose root mean square(RMS)values were over 0.3,not for LASIK,were randomly divided into two groups.One group 20 patients 40 eyes were applied conventional LASEK with Planoscan,the other 20 patients 40 eyes were applied wavefront guided LASEK with Zyoptix.Total corneal,coma and spherical aberration values were measured by Zywave aberrometer preoperatively and 1 month and 3 months postoperatively for all eyes.·RESULTS:There was no significant difference in higher-order aberrations,trefoil aberrations and spherical aberrations before surgery(P>0.05).RMS value of high order aberrations with 6mm pupil increased compared with that before surgery.There was significant difference in higher-order aberrations,trefoil aberrations and spherical aberrations between two groups(P<0.05).In postoperative month 3,two groups had lower RMS values of coma and trefoil aberrations than in month 1,whereas Zyoptix LASEK had lower higher-order aberrations than Planoscan LASEK.·CONCLUSION:Wavefront guided LASEK had better results than LASEK with Planoscan in higher-order aberration changes.·

R779.63