目的:观察双手微切口超声乳化手术治疗年龄相关性白内障的安全性和有效性。方法:年龄相关性白内障患者42例42眼,所有患者均接受同一手术者使用Legacy20000(美国Alcon公司)采用双手操作技术进行超声乳化手术。观察手术前后视力、眼压、角膜散光度和角膜内皮细胞的变化,以及术中术后的并发症。结果:患者术后1d;1wk;3mo术眼的最佳矫正视力分别为0.67±0.11,0.81±0.14,0.83±0.12,与术前相比,均有显著提高(P<0.01)。术后1d;1wk;3mo术眼的平均眼压分别为12.44±4.70,13.56±3.20,12.90±2.00mmHg,与术前相比,没有统计学的差异(P>0.05);术后1d;1wk;3mo术眼的平均角膜散光分别为1.23±0.62D(P<0.01),0.97±0.53D(P<0.05),0.65±0.47D(P=0.24),手术后第1d以及第1wk,术眼的散光较术前相比有显著性增加,术后3mo时,与术前相比无统计学意义;术后3mo角膜内皮密度为2235.06±418.43个/mm2,角膜内皮细胞的丢失率为(11.90±7.32)%。本组所有病例,术中、术后均没有发生严重的手术并发症。结论:双手微切口技术治疗年龄相关性白内障是安全有效的。

·AIM:To observe the clinical effectiveness of two-hand phacoemulsification cataract surgery for age-related cataract.·METHODS:Totally 42 patients 42 eyes with age-related cataract underwent two-hand phacoemulsification cataract surgery using the Legacy 20000(Alcon Inc.U.S.)by the same surgeon.Vision before and after surgery,intraocular pressure(IOP),corneal astigmatism and the change of corneal endothelial cell,and postoperative complications were observed.·RESULTS:The best-corrected visual acuity was 0.67±0.11,0.81±0.14,0.83±0.12 in postoperative day 1,week 1,month 3,respectively,and they were significantly increased compared with baseline(P<0.01);The average IOP were 12.44±4.70mmHg,13.56±3.20mmHg,12.90±2.00mmHg in postoperative day 1,week 1,month 3,and there were no statistical differences compared with preoperative(P>0.05);The average corneal astigmatism were 1.23±0.62D,0.97±0.53D,(P<0.01,P<0.05)in postoperative day 1 and week 1 and they were significantly increased compared with baseline(P<0.01),whereas there were no statistically differences in postoperative month 3(0.65±0.47D,P=0.24).In postoperative month 3 corneal endothelial density was 2235.06±418.43/mm2,and the loss rate of corneal endothelial cell was(11.90±7.32)%.All patients were without serious complications postoperatively.·CONCLUSION:Two-hand micro-incision for age-related cataract is a safe and effective method.·

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