目的:观察早产儿眼球生物学指标及屈光状态随年龄变化的规律。方法:早产儿218例、足月儿76例分别在出生后1,4,8和12mo进行A超检查,记录眼轴长度、前房深度、晶状体厚度、玻璃体腔长度;并在8和12mo进行睫状肌麻痹检影验光,记录球镜度;分析眼球生物学指标及屈光状态随年龄变化规律。结果:随年龄增长,无论早产儿及足月儿前房深度、玻璃体腔长度、眼轴长度均逐渐增大;晶状体厚度逐渐减小。出生初期,早产儿较正常儿前房深度浅,玻璃体腔长度及眼轴长度短。出生后随年龄增长,早产儿玻璃体腔长度和眼轴长度生长较足月儿快;但前房深度和晶状体厚度改变无明显差异。结论:出生时早产儿较正常儿眼球各项生物学指数发育差,随年龄增长,早产儿正视化较足月儿快,与眼轴生长有关。

AIM:To evaluate development of the ocular optical components and refractive error in premature infants and full term infants.·METHODS:Anterior chamber depth,lens thickness,and posterior segment length were measured by A-scan ultra-sonography in 218 premature infants and 76 full term infants 1,4,8,12 months after birth. The spherical equivalent refractive error was measured by cycloplegic retinoscopy 8,12 months after birth. ·RESULTS:Anterior chamber depth,posterior segment length and axial length were growing while the lens thickness decreasing with age;Anterior chamber depth,posterior segment length and axial length in premature infants were smaller than that of the full term infants at early age after birth; Posterior segment length and axial length showed greater increase in premature infants than full term infants; but no difference between the anterior chamber depth and the thickness of the lens. ·CONCLUSION:Optical components are immature at early age after birth but grow more rapidly with age in premature infants than that in full term infants,which contribute to the emmetropization development.

R77

中国湖南省科技厅资助项目(No.2007SK3076)~~