目的:分析青岛市开发区社区人群糖尿病性视网膜病变临床流行病学状况及其早期干预。方法:免费普查社区登记的确诊糖尿病患者600例,进行眼科检查,并对检查结果进行统计学分析,及对确诊为糖尿病性视网膜病变病例进行早期干预及治疗。结果:为600例糖尿病患者进行眼科检查,检出糖尿病性视网膜病变107例,患病率17.8%。并对这107例患者进行眼底荧光造影检查,其中确诊病例中有非增殖期病变者79例(73.8%),增殖期病变28例(26.2%)。对糖尿病病程、血糖控制情况、血压、血脂、糖尿病肾病的相关因素进行分析,在确诊的糖尿病视网膜病变患者中,糖尿病病程<10a者12例(11.2%),>10a者95例(88.8%);合并高血压者75例(70.1%);合并高血脂者66例(61.7%);合并糖尿病肾病者37例(34.5%)。结论:通过分析得出糖尿病病程长、空腹血糖高、合并高血压、高血脂、及糖尿病肾病者均属糖尿病视网膜病变发生的高危人群,高危糖尿患者群的密切监测及定期眼底检查是社区患者防治糖尿病视网膜病变的关键。

AIM:To analyze the clinical epidemiology of diabetic retinopathy and its early intervention in economic and technological development zone of Qingdao.·METHODS:Totally 600 patients with diabetes underwent free screening and the examination of ophthalmic fundus in community. The early intervention and treatment were performed for diagnosed diabetic retinopathy patients.·RESULTS:Totally 600 patients with diabetes underwent eye examinations,and the detection rate of diabetic retinopathy was in 17.8%(107 cases);And diagnosed 107 patients were performed the fundus fluorescein angiography,including 79 patients with non-proliferative lesions(73.8%) and 28 patients with proliferative lesions,(26.2%).The duration time,glycemic control,blood pressure,blood lipids,diabetes,kidney disease related factors were analyzed. Diabetic retinopathy patients,duration time below 10 years were in 12 cases,accounting for 11.2% and above 10 years in 95 cases,accounting for 88.8%; with hypertension were in 75 cases,accounting for 70.1%; combined hyperlipidemia in 66 cases,accounting for 61.7%; diabetic nephropathy in 37 cases,accounting for 34.5%.·CONCLUSION:The long duration time,fasting hyperglycemia,hypertension,hyperlipidemia,diabetes mellitus and diabetic nephropathy are main high-risk factors of retinopathy,and close monitor and regular fundus examination are key factors for prevention and treatment of diabetic retinopathy.

中国青岛市经济技术开发区科技局科研立项基金资助项目(No.2008-2-19)~~