目的:研究Verisyse虹膜固定型人工晶状体植入治疗高度近视中长期的有效性和安全性。方法:高度近视患者37例56眼植入Verisyse虹膜固定型人工晶状体,术后随访4～7a,对手术前后的裸眼和最佳矫正视力、屈光状态、眼压变化、角膜透明度及角膜内皮计数、前房、瞳孔和虹膜、自然晶状体改变及患者满意度进行观察分析。结果:所有眼术中均顺利植入Verisyse虹膜固定型人工晶状体,术后各时间点裸眼视力及最佳矫正视力均明显提高且保持稳定,各时间点角膜内皮细胞计数变化无统计学意义,随访期间无角膜内皮失代偿、顽固的色素膜炎、白内障、青光眼及视网膜脱离等严重并发症发生。结论:Verisyse虹膜固定型人工晶状体治疗高度近视是安全和有效的,能够显著提高裸眼视力及最佳矫正视力而并发症较少,对于不适合角膜手术的高度或超高度近视患者是一种比较理想的选择。

AIM:To evaluate the medium and long-term performance of the Verisyse iris-fixated phakic intraocular lens implantation for patients with high myopia.METHODS:Fifty-six eyes of 37 patients with high myopia who underwent the Verisyse iris-fixated phakic intraocular lens implantation from 2003 to 2006 were analyzed.The mean spherical equivalent was preoperatively(-16.62±3.70) DS,ranged from-10 to-28.5DS.Uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),manifest refraction,corneal endothelial cell counting,intraocular pressure and complications were evaluated.RESULTS:The implantation was successful in all of 56 eyes.Compared with preoperative clinical data,UCVA,BCVA and spherical equivalent were improved significantly after surgery.The results remained stable with in 4-7 years follow-up.The changes of corneal endothelial cell counting was not significant at each time point.All corneas remained clear throughout the study.No serious complications such as progressive endothelial cell loss,persistent uveitis,glaucoma,cataract or retinal detachment were observed.CONCLUSION:Medium and long-term results demonstrate that the implantation of the Verisyse iris-fixated phakic intraocular lens for the high myopia is a stable,effective,predictable and safe method with few complications.The method is an alternative to corneal surgery for the correction of refractive errors,especially in patients with severe ametropia unsuitable for excimer laser refractive surgery.

R779.6