目的:评估先天性上睑下垂患者的弱视发病情况。方法:在本横断面研究中,包括1岁以上的先天性上睑下垂患者100例(114眼)。最佳矫正视力小于10/10或两眼之间至少相差2/10者定义为弱视。年幼患者不能进行斯内伦视力表检测者,观察其注视情况。不同弱视患者的类型:1)屈光参差性弱视:散光性屈光参差≥1.00D;远视性球镜屈光参差≥1.00D,近视性球镜屈光参差≥-3.00D(睫状肌麻痹);2)斜视性弱视,3)形觉剥夺性弱视(SDA)。观察弱视的总发病率及类型,并对单侧和双侧上睑下垂患者进行比较。结果:弱视的发生率在上睑下垂患者为39/114(34.2%),其具体原因:屈光参差性弱视占29.8%,SDA占10.5%,斜视性弱视4.3%,严重的上睑下垂患者弱视发病率更高,视轴遮盖者(OA)占76%,而视轴未遮盖者只占22%。在视轴遮盖的单侧眼睑下垂患者,散光屈光参差性弱视发生率更高,在双侧眼睑下垂至少1眼视轴遮盖者,球镜屈光参差性弱视发生率更高。无论单侧和双侧上睑下垂,如果有视轴遮盖,则SDA比较多见。结论:由于屈光参差性弱视比SDA发生率更高,关注导致的弱视所有原因对于预防儿童上睑下垂所致的弱视极其重要。

·AIM:To study the frequency of amblyogenic factors in patients with congenital ptosis.METHODS:In this cross-sectional study,114 eyes of 100 patients with congenital ptosis more than 1 year old were included.Amblyopia was defined as best-corrected visual acuity(BCVA)less than 10/10 or a difference between the two eyes of at least 2/10.In patients too young to be measured by the linear Snellen E test,fixation behavior was observed.Different types of amblyopia were assessed for each patient as:1)anisometropic amblyopia:astigmatic anisometropia≥ 1dpt,hyperopic spherical anisometropia≥ 1dpt,myopic spherical anisometropia≥-3dpt(with cycloplegia);2)strabismic amblyopia,and 3)stimulus deprivation amblyopia(SDA).Then the total incidence of amblyopia and each type of it were obtained.Patients with uni-and bi-lateral ptosis were also compared.RESULTS:The incidence of amblyopia in ptotic eyes was 39/114(34.2%),and for each specific cause was refractive amblyopia in 29.8%,SDA in 10.5%,strabismic amblyopia in 4.3%.Amblyopia was more frequent in severe ptosis,76% in patients with covered optical axes(OA),compared to non-covered OA(22.5%).In unilateral ptosis with covered OA,astigmatic anisometropic amblyopia was more frequent,and in bilateral ptosis with at least one eye covered OA,spherical anisometropic amblyopia was more frequent.In both unilateral and bilateral ptosis,SDA was more common if the OA was covered.CONCLUSION:As refractive anisometropic amblyopia is more prevalent than SDA,paying attention to all causes of amblyopia may be important in preventing amblyopia in a child with a ptotic eye.

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