微循环是无法直接观察和研究调查。视网膜提供了评估微循环非侵入性方法。目前,量化视网膜微血管变化的可靠方法存在。尤其,通过定量测量视网膜血管口径,提高了对视网膜动脉和小静脉口径和系统性因素的影响和临床意义的认识,大量研究证实AV,RV和AVR变化可能反映亚临床脑血管、心血管疾病和新陈代谢异常的临床前期改变。

·The microcirculation is relatively inaccessible to direct visualization and investigation.The retina offers a readily accessible site to noninvasively evaluate the microcirculation.Recently,reliable methods of quantifying retinal microvascular changes from retinal photographs have been developed.In particular,quantitative measurement of retinal vascular caliber has greatly increased knowledge of the clinical significance and influence of systemic factors on the retinal arteriolar and venular caliber.Recent studies have reported that the AV,RV and AVR may mirror preclinical structural changes in the subclinical cerebrovascular,cardiovascular and metabolic outcomes.

R774.1

中国山东省医药卫生科技发展计划重点基金资助项目（No.2009HD002）