目的:探讨原发性翼状胬肉两种治疗方法的疗效观察。方法:A组25例采用翼状胬肉切除联合丝裂霉素术治疗,B组10例采用自体球结膜+角膜缘干细胞移植术治疗。根据角膜创面恢复、结膜伤口愈合、胬肉有无复发进行观察。结果:A组患者术后角膜上皮第3～7d恢复,结膜充血10～15d消退,3例复发;B组患者术后角膜上皮第2d恢复,结膜充血7～10d消退,1例复发。结论:翼状胬肉切除术联合丝裂霉素和自体球结膜+角膜缘干细胞移植术都能降低胬肉复发率,二者相比较,自体球结膜+角膜缘干细胞移植术优于翼状胬肉切除联合丝裂霉素。

·AIM:To discuss two different surgical treatments and effects for pterygium.METHODS:The patients were divided into two groups.25 patients with pterygium surgical excision combined with mitomycin C treatment were in group A,10 patients treated with autologous conjunctival limbal stem cell transplantation and corneal limbal stem cell transplantation in group B.The corneal wound healing,conjunctival wound healing,and recurrence of pterygium were observed.RESULTS:In group A,the recovery of corneal epithelium occurred 3-7 days after surgery,conjunctival congestion was subsided 10-15 days after surgery,and 3 cases recurred.In group B,the recovery of corneal epithelium occurred 2 days after surgery,conjunctival congestion was subsided 7-10 days postoperatively,and 1 case was recurrent.CONCLUSION:Pterygium excision combined with mitomycin and autologous conjunctival limbal stem cell transplantation and corneal limbal stem cell transplantation can reduce the recurrence rate of pterygium.The conjunctival and corneal limbal stem cell transplantation is better compared with pterygium excision combined with mitomycin.

R777.33