目的:探讨减少近视患者行准分子激光原位角膜磨镶术(laser in situkeratomileusis,LASIK)术后干眼症状的方法。方法:对659例1311眼行LASIK治疗的近视患者行术前筛查及羧甲基纤维素眼液点眼临床干预,分别观察术前、术后1wk;1,3和6mo的干眼症状,包括干涩感、异物感等,并行角膜荧光素染色检查、泪膜破裂时间测定及泪液分泌试验。结果:术前干眼者术后1wk;1,3和6mo干眼症为45.0%,31.7%,15.1%和4.1%;术前无干眼者术后干眼症分别为32.8%,19.5%,8.1%和1.9%。结论:采取术前筛查和药物干预是减少LASIK术后干眼的有效措施。

·AIM:To study the methods of reducing dry eye after laser in situ keratomileusis(LASIK)in myopic eyes.METHODS:LASIK was performed in 1311 myopic eyes.The symptoms of dry eye preoperatively and 1 week,1 month,3 and 6 months after operation were observed,fluorescein staining(FL),Schirmer Ⅰ test,tear break-up time(BUT)were performed.RESULTS:Dry eye occurred at percentage of 45.0% 1 week,31.7% 1 month,15.1% 3 months and 4.1% 6 months after the operation for preoperative dry-eye group.For preoperative non-dry-eye group,the percentage was 32.8% 1 week,19.5% 1 month,8.1% 3 months and 1.9% 6 months after the operation.CONCLUSION:Dry eye can be prevented and treated effectively by preoperative screening and drug intervention.

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