目的:观察复明片配合人工泪液局部滴眼治疗肝肾阴虚型干眼症的临床疗效。方法:将符合肝肾阴虚型干眼症诊断标准的患者,随机分为治疗组和对照组。治疗组采用口服复明片和局部滴用玻璃酸钠滴眼液治疗;对照组采用单纯滴用玻璃酸钠滴眼液治疗。根据临床症状和基础泪液分泌试验、泪膜破裂时间、角膜荧光素钠染色等检查进行评分。随机抽取干眼症患者60例,治疗组和对照组各30例60眼,治疗观察2mo。结果:两组治疗后BUT,SⅠt、角膜荧光素染色与治疗前比较,差异均有统计学意义(P<0.05或P<0.01),且治疗后治疗组上述指标变化程度明显优于对照组(P<0.01);治疗组总有效率93.3%,对照组总有效率75.0%,治疗组疗效明显优于对照组(P<0.01)。结论:复明片联合人工泪液局部点眼治疗干眼症疗效较单纯使用人工泪液滴眼疗效好。

·AIM:To observe the clinical efficacy of oral fuming tablet,sodium hyaluronate eye drops for dry eye syndrome of deficiency of liver-yin and kidney-yin type.·METHODS:The randomly selected 60 patients(120 eyes)with dry eye syndrome of deficiency of liver-yin and kidney-yin type were randomly divided into treatment group and control group,each of 30 patients(60 eyes),Treatment group were treated with oral fuming tablet plus sodium hyaluronate eye drops;control group were treated with sodium hyaluronate eye drops only.Treatment and observation lasted for two months.It was based on clinical symptoms and Schirmer I test(SⅠt),break-up time(BUT),corneal fluorescein staining and other tests to score.·RESULTS:Compared with before treatment,the differences of test results of BUT,SⅠt,corneal fluorescein staining of two groups after treatment were statistically significant(P<0.05 or P<0.01).The total effective rate was 93.3% in the treatment group,it was 75.0% in the control group.The treatment group was superior to the control group(P<0.01),with statistical significance.·CONCLUSION:The clinical efficacy of oral fuming tablet combined with sodium hyaluronate eye drops for dry eye syndrome of deficiency of liver-yin and kidney-yin type is superior to that of the simple use of sodium hyaluronate eye drops.·

R276.7