目的:观察软性角膜接触镜治疗角膜溃疡穿孔的临床疗效。方法:对24例24眼角膜溃疡穿孔的患者采用配戴软性角膜接触镜治疗。其中细菌性14例14眼,病毒性8例8眼,真菌性2例2眼。戴镜期间根据不同病因选择联合用药,角膜镜配戴1wk清洗,3wk更换,角膜愈合后摘镜,随诊复查。结果:角膜溃疡穿孔患者24例24眼戴镜后1～2d前房均形成,5～10d后角膜上皮覆盖,角膜基质层纤维网状支架形成,20～32d角膜溃疡愈合,穿孔区密闭良好。患者视力有不同程度提高。结论:软性角膜接触镜是一种安全有效的角膜溃疡穿孔的辅助治疗方法。

·AIM:To investigate the clinical effect of soft corneal contact lens for perforated corneal ulcer.·METHODS:Twenty-four cases 24 eyes with perforated corneal ulcer were treated by soft corneal contact lens,in which fourteen cases 14 eyes were with bacterial corneal ulcer,eight cases 8 eyes were with viral corneal ulcer,two cases 2 eyes were with fungual corneal ulcer.Combination therapy was chosen according to different causes of disease.The soft corneal contact lens was cleaned after one week,changed after three weeks until ulcer healed.·RESULTS:In 24 cases 24 eyes of perforated corneal ulceration patients,anterior chamber was formed after 1-2 days,corneal epithelium covered,corneal stromal layer fiber mesh scaffolds formed after 5-10 days,20-32 days later corneal ulcer healed perforated area closed well.Vision had improved with different degrees.·CONCLUSION:It is a safe and effective adjunctive therapy to cure perforated corneal ulceration with soft corneal contact lens.·

R772.21