目的:分析Densiron68在玻璃体视网膜手术中应用的并发症。方法:玻璃体视网膜疾病患者18例19眼入选,其中PVRC1至PVRD2者12眼,糖尿病视网膜病变1例2眼,4眼为复发性视网膜脱离,合并病理性近视9眼,外伤后视网膜脱离1眼。患者年龄19～78(平均47.63±21.93)岁,术前术后常规行视力、眼压的测定,眼前后段检查、OCT、角膜内皮镜及B超等检查。手术方式包括:Densiron68填充术及硅油取出术。Densiron68的充填时间是44～141(平均76.00±23.84)d。取油后的随访时间为40～197(平均95.74±44.58)d。结果:取油后,16眼(84.21%)达到稳固的视网膜复位效果,1眼(5.26%)在Densiron68充填第12d时出现了复发性视网膜脱离,2眼(10.53%)取油后出现复发性视网膜脱离;术后视力较术前改善14眼(73.68%);术后并发症主要有短暂的前房反应、硅油乳化、晶状体后囊膜混浊、术后一过性高眼压和瞳孔阻滞性青光眼。结论:Densiron68作为玻璃体视网膜疾病(尤其是下方视网膜脱离)的眼内填充物,可以明显提高患者视网膜的解剖复位率和视力,但填充后短期内并发症发生率较高。

AIM:To evaluate the clinical complications of Densiron68 as an intraocular tamponade in the vitreoretinal surgery. METHODS:Nineteen eyes of 18 patients aged 19 years to 78 years with complex retinal detachment were included.Initial evaluation included present ophthalmologic and general medical history, determination of the best corrected visual acuity, intraocular pressure (IOP) measureed by non-contact tonometer, detailed slit lamp and fundus examination. Surgery was performed as a standard three-port, pars plana vitrectomy. At removal surgery,15 eyes of the posterior peplos discission was performed. Mean duration of the Densiron68 endotamponade was 76.00±23.84 days,mean follow-up time after removal was 95.74±44.58 days. RESULTS:After Densiron68 removal, 16 eyes (84.21%) showed a stable reattached retinal without further interventions , while, in 1 eye (5.26%), recurrent retinal redetachment appeared during endotamponade. Two eyes (10.53%) developed redetachment after Densiron68 removal. Visual acuity was improved in 14 eyes (73.68%).Side effects included temporary inflammatory reaction, silicon oil emulsification, posterior capsular opacification, temporary high intraocular pressure and pupillary block glaucoma. CONCLUSION:The results showed that Densiron68 as an endotamponade was effective and security ,however, incidence of complications was higher shortly after tamponade.

R779.6