目的:分析羊膜移植治疗翼状胬肉失败的原因。方法:回顾性总结2006-09/2009-12期间施行羊膜移植治疗翼状胬肉194眼(其中初发性翼状胬肉120眼,复发性翼状胬肉74眼)的临床效果,分析手术失败的原因。结果:随访15～36mo,羊膜移植片溶解9眼(4.6%),翼状胬肉复发30眼(15.5%)。结论:移植床表面不干净不平滑、植片下积血及植片缝合不牢固是羊膜植片溶解的主要因素。羊膜植片溶解、胬肉切除不彻底、手术创伤及术后炎症刺激反应是翼状胬肉复发的重要原因。

AIM:To analyse the failure reason of fresh amniotic membrane transplantation in treatment of pterygium. METHODS:The clinical efficacy of 194 eyes of newly developed pterygium (120 eyes) and recurrent pterygium(74 eyes), which were performed fresh amniotic membrane transplantation from September 2006 to December 2009, were retrospectively investigated.The failure reason was analysed. RESULTS:Amniotic membrane of 9 eyes (4.6%) melted and pterygium of 30 eyes recurred. The post-operative follow-up periods were 15 to 36 months. CONCLUSION:That transplantation bed surface is not smooth or clean, hemorrhage under the graft and that graft suture is not solid are the main factors of dissolved amnion graft. Amniotic membrane dissolution, inexhaustive excision, surgical trauma and postoperative inflammatory stimulation and important reasons in recurrent pterygium.

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