目的:了解社区中老年人群年龄相关性黄斑变性(AMD)的患病情况。方法:流行病学现况调查。选择户籍在西长安街社区50岁及以上人群,采用逐户上门登记的方法确认入选合格人群。对所有入选人员应用问卷调查法询问健康、医疗等一般状况和生活习惯,并进行既定的眼部检查,主要内容包括裸眼视力、小孔镜视力、非接触眼压测量、裂隙灯检查、检眼镜检查、免散瞳眼底照相等。采用年龄相关性黄斑病变临床分级系统对受试者眼底像结果进行评估。结果:50岁以上户籍人口数2833人,共完成2410例受试者的检查,应答率85.07%。早期AMD患病率为2.98%(70/2348例),晚期AMD患病率为0.30%(7/2348例),其中晚期渗出性病变占0.17%(4/2348例)。AMD患病率随年龄增长呈增加的趋势。因AMD导致的单眼盲占6.49%(5/77例),双眼盲占2.60%(2/77例)。结论:北京市西长安街社区50岁以上人群年龄相关性黄斑变性患病率与国内外多数研究结果相似,早期病变占多数,对年龄相关性黄斑变性的防治将是今后社区防盲工作的重点之一。

AIM:To evaluate the prevalence of age-related macular degeneration(AMD) in elderly population in urban area of Beijing.METHODS:Epidemiology survey.Citizens of more than 50 years old in the community of Xi Chang’an street of Beijing were recruited.The targeted subjects were picked up by door-to-door and a questionnaire about healthy state,medicine,life habits et al was answered.The comprehensive ophthalmic examinations,including visual acuity,pinhole visual acuity,non-contact intraocular pressure test,slit-lamp,ophthalmoscopy and non-mydriatic fundus photography were performed.Colorful fundus photography was taken by a trained ophthalmologist.AMD was graded on fundus photography following Clinic Age-Related Maculopathy System.RESULTS:A total of 2833 citizens of more than 50 years old had dwelled in the community and 2410 participated in the investigation,meaning a response rate of 85.07%.Early AMD was present in 70(2.98%) of 2348 subjects,late AMD in 7(0.30%) of 2348 subjects,and exudative AMD in 4(0.17%) of 2348 subjects.Monocular blindness caused by late AMD accounted for 6.49%(5/77 subjects) and binocular blindness 2.60%(2/77 subjects) of the study population.The prevalence of AMD increased with age.CONCLUSION:The prevalence of AMD in the community of Beijing is similar to reports of most studies both international and domestic,early AMD is majority of pathology,which is one of major tasks of blindness prevention in the community.

R774.5

中国北京市西城区科委资助项目(No.2007033)~~