目的:观察复方樟柳碱Ⅱ号联合苦碟子注射液治疗前部缺血性视神经病变(AION,非颞动脉炎型)的临床效果。方法:临床确诊为AION(非颞动脉炎型)的患者38例38眼,随机将其分为A组(常规用药组):采用高压氧;口服醋氮酰胺片、维生素B1,B12、复方丹参片;静脉滴注丹参注射液20mL。B组为(复方樟柳碱Ⅱ号联合苦碟子组):除高压氧;口服醋氮酰胺片、维生素B1,B12、复方丹参片,另加用复方樟柳碱Ⅱ号,在患侧颞浅动脉旁皮下注射联合静脉滴注苦碟子注射液20mL。均以10d为一疗程。每天观察视力,眼底情况,治疗前后予以视野、FFA检查对比。结果:B组视力提高程度、时间均明显优于A组,两组间差异具有统计学意义(P<0.05)。B组视力视野、FFA检查均明显优于A组,两组间差异具有统计学意义(P<0.05)。结论:复方樟柳碱Ⅱ号联合苦碟子注射液治疗AION(非颞动脉炎型)是一种安全、高效的治疗组合。

AIM:To explore the clinical application of complex anisodine Ⅱ combined with ixeris sonchifolia in treating anterior ischemic optic neuropathy(AION)(non-temporal arteritis type).METHODS:Thirty-eight patients(38 eyes) who were clinically diagnosed as AION(non-temporal arteritis type) were randomized into two groups.Group A used routine treatment,including hyperbaric oxygen;orally taken acetazolamide,vitamin B1,vitamin B12,compound salvia miltiorrhiza tablet;intravenous taken salvia miltiorrhiza injection 20mL.Group B used the routine treatment plus complex anisodine II subcutaneous injection beside the affected side arteriae temporalis superficialis combined with intravenous ixeris sonchifoila 20mL.The period of treatment was 10 days for the both groups.Visual acuity and fundus oculi were examined every day.Preoperative and postoperative visual field and FFA were compared.RESULTS:Compared with group A,group B had quick and better improvement of visual acuity(P<0.05).And the group B had better results of visual field and FFA test,when compared with group A(P<0.05).CONCLUSION:The use of complex anisodine II combined with ixeris sonchifolia in treating AION(non-temporal arteritis type) is safe and efficient.

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