目的:观察比较慢性闭角型青光眼、原发性开角型青光眼、正常眼压性青光眼以及正常人的眼压,眼脉动幅度特征及其相关性。方法:收集临床确诊为慢性闭角型青光眼患者19例,原发性开角型青光眼18例,正常眼压性青光眼15例,正常人20例,用动态轮廓眼压计测量其眼压及眼脉动幅度,同时测量患者的血压及心率。运用SPSS14.0进行统计学分析。结果:慢性闭角型青光眼组的平均眼压为25.42±9.95mmHg,OPA为3.84±0.88mmHg;原发性开角型青光眼组的平均眼压为23.12±5.47mmHg,OPA为3.29±0.90mmHg;正常眼压性青光眼组的平均眼压为16.52±2.23mmHg,OPA为1.85±0.47mmHg;正常人组的平均眼压为16.31±2.67mmHg,OPA为2.47±0.80mmHg。前两组与后两组之间的眼压存在着显著性差异,四组之间的OPA均存在统计学差异。四组患者的眼压及眼脉动幅度之间存在着弱相关性,但无统计学意义。结论:慢性闭角型青光眼、原发性开角型青光眼及正常眼压性青光眼的OPA之间存在统计学差异,眼压与OPA之间存在弱相关性,但无统计学意义。

AIM:To investigate the feature of intraocular pressure(IOP) and ocular pulse amplitude(OPA) measured by dynamic contour tonometer(DCT) in the chronic angle-closure glaucoma(CACG),the primary angle-open glaucoma(PAOG),the normal tension glaucoma(NTG) and the healthy controls and to analyze the relation between the IOP and OPA.METHODS:Nineteen cases of chronic angle-closure glaucoma,18 cases of primary angle-open glaucoma,15 cases of normal tension glaucoma and 20 cases of healthy controls were taken into the measure.IOP,OPA were measured by DCT at the same time.One eye of each patient were taken into analysis randomly.All the patients accepted the blood pressure and the heart rates measure at the same time.The results were taken into analysis by SPSS 14.0.RESULTS:The mean IOP were 25.42±9.95mmHg,23.12±5.47mmHg,16.52±2.23mmHg and 16.31±2.67mmHg in CACG,PAOG,NTG and normal controls group.There were significant differences of IOP between the CACG group and NTG group(P<0.001).It was also observed between the PAOG group and NTG group(P=0.003).The mean OPA were 3.84±0.88mmHg,3.29±0.90mmHg,1.85±0.47mmHg and 2.47±0.80mmHg in CACG,PAOG,NTG and normal controls group.Significant difference of OPA was observed between the CACG group and the PAOG group(P=0.038).The OPA of the NTG group had significant difference with that of the CACG,the PAOG and the normal controls group(P<0.01,P<0.01,P=0.039).There were low correlations between the IOP and OPA in four groups.CONCLUSION:The statistical differences of OPA were among the CACG,the PAOG,the NTG and the healthy controls.There was low correlation between the IOP and OPA.

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