目的:比较近年青光眼患者在青光眼类型、发病年龄和性别分布的差异,并与以往的资料作比较,以了解青光眼内部构成的变化趋势,为青光眼的防治研究提供新的流行病学资料。方法:收集华西医院眼科2009-01/12所有青光眼住院患者病历共577例,根据出院诊断分为原发性闭角型青光眼(PACG),原发性开角型青光眼(POAG),先天性青光眼,继发性青光眼,并将其与1978-01/1981-12,以及2001-01/2002-12青光眼住院患者971例进行比较。结果:2009年间,原发性青光眼占当年青光眼住院患者总数的60.2%所占比例下降;POAG占原发性青光眼的27.4%,在原发性青光眼中的构成比有所上升;PACG中位数年龄为62.8,总体有所增大,POAG中位数年龄为48,无明显变化;POAG中女性患者比例增加;2009年继发性青光眼占当年青光眼住院患者总数的33.4%,比例显著较往年增加。结论:POAG在原发性青光眼中的构成比有所上升,继发性青光眼患者显著增加。

AIM:To investigate the type of glaucoma,age and gender distribution and compare them with previous data for the prevention and treatment of the disease.METHODS:Totally 577 hospitalized glaucoma patients in West China Hospital from January 2009 to December 2009 were classified by their diagnosis,gender and age to analyze the changing feature of proportion,and compared with the 971 cases from January 1978 to December 1981 and January 2001 to December 2001.RESULTS:During 1978-1981 and 2001-2002,primary glaucoma constituted 81.3% and 81.4% of all kinds of glaucoma,while it changed to 60.2% during 2009.During 1978-1981 and 2001-2002,primary open-angle glaucoma(POAG) constituted 11.3% and 23.9% of primary glaucoma,and the rate increased to 27.4% in 2009.The median age of primary angle closure glaucoma(PACG) was 62.8,which was increased,and the median age of POAG was 48,without obvious changes.Proportion of women increased in POAG patients.During 1978-1981 and 2001-2002,secondary glaucoma constituted 12.7% and 14.1% of all kinds of glaucoma,while it increased to 33.4% during 2009.CONCLUSION:Proportion of POAG in primary glaucoma seems to have risen.Secondary glaucoma increases significantly.

R775