在脉络膜新生血管(choroidal neovascularization，CNV)的发生发展过程中, 许多生长因子发挥了一定的作用。近来发现胰岛素样生长因子-1（insulin-like growth factor-1，IGF-1）不仅参与胚胎发育、创伤修复和肿瘤生长等过程的调节, 而且还是一种眼内促生长的促血管生成因子，参与了CNV的形成。现对IGF-1与CNV形成关系的研究进展作一综述。

The occurrence and development of choroidal neovascularization (CNV) are related to various growth factors. Recently, insulin-like growth factor-1(IGF-1) which plays an important role in embryonic development, repair in trauma and tumor growth is reported to be an angiogenesis factor in ocular and takes part in the formation of CNV. Current study on effects of IGF-1 in CNV is analyzed in this paper.