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[摘要]
目的:探讨应用激素治疗急性前葡萄膜炎的方法、疗效,以减少复发率。 方法:对142例急性前葡萄膜炎病例常规给予局部结膜下注射地塞米松2~3mg,1次/d。同时局部点用典必殊及1g/L双氯芬酸钠眼药水。个别病例经局部激素治疗后不能控制病情,则予口服大剂量强的松80~100mg,逐日减量10~20mg,3~5d停药,一般不超过1wk,继续局部激素治疗。 结果:全部病例于30d内痊愈,未出现全身并发症,6mo内无1例复发,1a内复发率14.8%(21例)。 结论:大多数急性前葡萄膜炎不需全身激素治疗,同时适当延长疗程可能对降低复发率有效。
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[Abstract]
AIM:To explore the methods and efficacy of hormone therapy of acute anterior uveitis, to reduce the recurrence rate. METHODS:Totally 142 cases of acute anterior uveitis were given conventional topical subconjunctival injection of dexamethasone 2-3mg, 1 time/day,at the same time local allusions of TobraDex and 1g/L diclofenac sodium eye drops. Individual cases could not control the disease by topical steroid therapy, then resorted to high-dose oral prednisone 80-100mg, 10-20mg daily reduction, withdrawal afer 3-5 days, generally not more than 1 week, and continued topical steroid therapy. RESULTS: All patients healed within 30 days, without any systemic complications, without recurrence within six months, the relapse rate was 14.8% ( 21 cases) within a year. CONCLUSION:The majority of acute anterior uveitis need not systemic hormone therapy, at the same time prolonged courses of treatment may be effective to reduce the recurrence rate.
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