准分子激光矫正屈光不正主要是在角膜上进行，在制作角膜瓣和进行激光切削的过程中不可避免会造成角膜神经的损伤，手术方式、切削深度和角膜瓣的厚度不同对角膜神经造成的影响也有差异。神经损伤后角膜感觉下降或消失，影响创口愈合和手术质量。我们主要就当前主流屈光手术方式对角膜神经损伤的机制以及屈光手术后促进角膜神经再生的因素做一综述，为进一步提高手术质量提供依据。

Several laser refractive surgical procedures have been used to reshape the cornea to correct refractive error. During the procedures of making corneal flap and ablation, it would inevitably make some damages to corneal nerves. The procedures of laser surgery, the depth of ablation and the thickness of corneal flap play important roles in the damage of corneal nerves. In this review we study the mechanism of corneal nerve damage caused by several main laser eye surgery and the factors which may accelerate the regeneration of corneal nerve, in order to improve the surgical quality.