目的：观察那他霉素联合5g/L活力碘治疗真菌性角膜溃疡的临床疗效。 方法：对38例38眼真菌性角膜溃疡采用那他霉素联合5g/L活力碘及相关抗真菌药物（斯皮仁诺等）治疗，并进行回顾性分析。 结果：经过那他霉素联合5g/L活力碘及斯皮仁诺（伊曲康唑）等药物的治疗，治愈30眼，好转7眼，1眼因角膜穿孔致真菌性眼内炎而丧失眼球。治愈率为79%，有效率97%。 结论：那他霉素联合5g/L活力碘及斯皮仁诺（伊曲康唑）等药物治疗真菌性角膜溃疡是安全有效，简便实用的。

AIM:To observe the clinical effect of natamycin joint 5g/L povidone iodine for treatment of fungal corneal ulcer. METHODS:Totally 38 cases (38 eyes) of fungal corneal ulcer used natamycin joint 5g/L povidone iodine and related antifungals (Sporanox, etc.) for treatment, and were analyzed retrospectively. RESULTS:After treatment with natamycin joint 5g/L povidone iodine and Sporanox (itraconazole) and other drugs, 30 eyes cured, 7 eyes improved, 1 eye lost eyeball due to corneal perforation and fungal endophthalmitis.The cure rate was 79%, effective rate was 97%. CONCLUSION: Natamycin joint 5g/L povidone iodine and Sporanox (itraconazole) and other drugs for treatment of fungal corneal ulcer is safe and effective, simple and practical.