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目的:探讨白内障术后眼内炎的治疗方案及效果。 方法:对我院2006-01/2010-12白内障摘除术+人工晶状体植入术的21973例28722眼患者的资料(超声乳化20937例27521眼,囊外摘除术1036例1201眼)进行回顾性分析。 结果:在全部术眼中,感染性眼内炎11眼,感染率为004%,9眼发生于超声乳化术后,2眼发生于白内障囊外摘除术后。共有5眼病原菌培养阳性,其中表皮葡萄球菌2眼,金黄色葡萄球菌,浅绿色气球菌,真菌各1眼。感染发生于白内障术后2wk以内者占73%(8/11),房水混浊或前房积脓者行前房灌洗+玻璃体腔注射万古霉素;前房积脓合并明显玻璃体混浊或经前房灌洗+玻璃体腔注射万古霉素治疗观察1~2d感染加重者行前房灌洗+玻璃体切割术。治疗后11眼均保住眼球。 结论:白内障术后眼内炎经常发生于白内障术后2wk以内,经及时有效的治疗可控制感染发展,保留部分有用视力;前房灌洗+玻璃体腔注射万古霉素必要时联合玻璃体切割术是有效的治疗方法。
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[Abstract]
AIM: To discuss the treatment perscription and effect of endophthalmitis after cataract surgery. METHODS: The clinical records of 21973 cases 28722 eyes(20937 cases 27521 eyes of phacoemulsification, 1036 cases 1201 eyes of extracapsular cataract extraction)with infective endophthalmitis after cataractopiesis and intraocular lens implants in our hospital from 2006 to 2010 were retrospectively analysed. RESULTS: There were 11 eyes of infectious endophthalmitis and the infection rate was 0.04%,9 eyes of which occurred after phacoemulsification, and 2 eyes of which occurred after extracapsular cataract extraction. 5 eyes showed positive results in pathogens cultures, included 2 eyes of staphylococcus epidermidis, 1 eye of staphylococcus aureus, 1 eye of light green aerococcus and 1 eye of fungus. 73%(8/11) of postoperative endophthalmitis occurred within 2 weeks after cataract surgery. Anterior chamber lavage and intravitreal injection of vancomycin were performed when aqueous humor was turbid or anterior chamber was full of empyema;anterior chamber lavage and an operation of vitrectomy were performed when the anterior chamber was full of empyema with obviously turbid vitreum, or when infection aggravated 1 to 2 days after lavaging the anterior chamber and injecting vancomycin into vitreous cavity. All of the 11 eyes kept eyeball after surgery . CONCLUSION: Endophthalmitis after cataract surgery usually occurs within 2 weeks after ocular surgery.Effective treatment of endophthalmitis after cataract surgery can effectively control bacteria and improve vision prognosis. Anterior chamber lavage and intravitreal injection of vancomycin combined with pars plana vitrectomy are effective to treat the infective endophthalmitis after cataract surgery.
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