目的：探讨内源性眼内炎的临床特征及治疗。 方法：对2005/2011年所收治的内源性眼内炎患者8例进行常规眼科检查，取前房水及玻璃体标本涂片和培养，血培养。给予局部及全身抗菌药物治疗，行玻璃体注药或(和)玻璃体切割术。观察病变特点及治疗效果。 结果：患者8例9眼中男6例7眼，女2例2眼，年龄45~78岁。患者可有前葡萄膜炎症表现，玻璃体炎性改变，5例患者病原菌培养阳性，3眼行玻璃体腔注射，6眼行玻璃体切割手术。经治疗，患者病情控制，6眼视力提高。 结论：内源性眼内炎根据病史、危险因素、临床表现以及实验室检查等综合进行诊断。局部+全身治疗可有效控制感染。

AIM:To analyze the clinical characteristics，diagnosis and treatment of endogenous endophthalmitis． METHODS:Participants were 8 cases (9 eyes)with endogenous endophthalmifis in Beijing Renhe Hospital from 2005 to 2011．All patients completed routine ophthalmic examination．Aqueous humor and vitreous body were smeared and cultured，blood culture．All cases received local and systemic antibiotic drug therapy，and were treated by intravitreal injection or/and vitrectomy． RESULTS:There were 6 males(7 eyes) and 2 females(2 eyes)，aged from 45 to 78 years．1 case had bilateral endophthalmitis．None of them had the history of ocular trauma or intraocular surgery．The main clinical manifestations included different degree of anterior uveitis，vitreous inflammations．5 of them were pathogen culture positive．2 eyes were treated by intravitreal injection，7 eyes received vitrectomy．Visual acuity was improved in 6 eyes． CONCLUSION:Synthetic diagnosis and treatment of endogenous endophthalmitis is very important．Vitrectomy and antibiotic therapy can control infection effectively．