目的：探讨玻璃体切割联合内界膜剥离术治疗黄斑裂孔性视网膜脱离的疗效和并发症。 方法：收集我院2009-09/2011-12黄斑裂孔性视网膜脱离住院患者22例22眼。均采用玻璃体切割联合内界膜剥离手术方式。随访观察术后1,2,3d;1wk;1mo的患者最佳矫正视力、眼压。并对患者年龄和患病病程与术后1mo最佳矫正视力进行统计学分析。 结果：行气体填充13例，行硅油填充9例。患者术后黄斑裂孔封闭率100%，视网膜均解剖复位。术后最佳矫正视力随术后恢复时间逐渐提高。眼压在术后1,2,3d有升高,7d后下降逐步恢复正常。患病病程＜6mo的患者较病程>6mo的患者术后视力恢复好。黄斑裂孔患者的术后1mo最佳矫正视力与患者年龄无相关性。 结论：玻璃体切割联合内界膜剥离术是治疗黄斑裂孔视网膜脱离的有效手术方式，可提高术后视力。

AIM:To analyse the outcome and complication of vitrectomy and internal limiting membrane peeling for macular hole with retinal detachment. METHODS:Twenty-two cases (22 eyes) were observed from September 2009 to December 2011.All the cases underwent vitrectomy and internal limiting membrane peeling. The best-corrected visual acuity and intraocular pressure were observed before and after operation.The data of first three days, a week and a month after operation were evaluated by statistical analysis. RESULTS:Thirteen cases underwent vitrectomy with C³F⁸ while the other 9 cases with silicon oil. The rate of anatomical closure was 100%.The best-corrected visual acuity was elevated gradually after operation. The intraocular pressure raised in first three days and went down after a week.The outcome was better in group with the course of the disease less than 6 months.There was no correlation between the best-corrected visual acuity of postoperative 1 month and patients age. CONCLUSION:Vitrectomy and internal limiting membrane peeling is effective for macular hole with retinal detachment.It can improve vision.

National Natural Science Foundation of China (No.81100649); Distinguished Young Talents in Higher Education Foundation of Guangdong, China(No.LYM10112)