目的：对近视眼患者存在的波前像差进行相关因素分析。 方法：用波前像差仪对前来我院行LASIK手术的115例218眼进行波前像差的检查，并进行常规角膜屈光手术的各项术前检查，同时用对比敏感度检查表进行对比敏感度的检查，将各项结果分别与波前像差进行相关性分析。 结果：像差成分以低阶像差为主，高阶像差有明显的个体差异，最大值是最小值的62倍；术前像差和瞳孔直径呈正相关关系，即随着瞳孔直径的增加高阶像差增加；高阶像差与中频区对比敏感度存在弱的负相关性；波前像差和患者的屈光度的高低有关系；随着散光度数的增加，波前像差增加。术前像差各成分和性别无显著相关性。 结论：近视眼患者的波前像差受患者具体条件的影响，个性化手术去除波前像差应考虑周全。

AIM:To investigate the related factors in the ocular aberrations induced by myopia. METHODS:The ocular aberrations of 115 cases ( 218 eyes ) were measured before laer in situ keratomileusis (LASIK) refractive surgery in our hospital by Zywave. Preoperative examinations included contrast sensitivity and wavefront aberrations for both eyes by Zywave (Hartmann-Shack wavefront aberrometer). RESULTS:About 89% of all in ametropia people was low order wavefront aberration (defocus and regular astigmatism),and 3^rd order and above were only about 11%, Individual difference was large in high order aberrations from 1.86 to 0.03.RMS was increased with the larger pupil zone. The correlations between the components of wavefront and contrast sensitivity were weak negative.There were no correlations between the RMS of high order aberration and diopter in eyes with myopic spherical errors below -6.00D, whereas in eyes with errors between -6.00D and -14.00D,the correlations were stronger.The RMS of 3^rd and 4^th order aberration were positively correlated with astigmatism. There was no obvious difference between female and male. CONCLUSION:Wavefront aberration of the myopia patients is affected by specific conditions, personalized surgical removal of the wavefront aberration should be thoughtful."