目的：评价胰岛素泵在糖尿病患者围手术期的应用价值。 方法：随即选择50例50眼需要进行玻璃体切除手术的糖尿病患者，分别应用胰岛素泵持续皮下输注（continuous subcutaneous insulin infusion, CSII）法（27例）和每日多次皮下注射胰岛素(multi-subcutaneous insulin injection, MSII)法（23例），根据血糖检测结果调整药物剂量，比较两种不同给药方法在血糖控制水平、血糖达标时间之间的差异。 结果：两组在手术治疗前、后皆能有效控制血糖至正常或基本正常水平，差异均有显著性(P<0.05)，但组间无差异；CSII组与MSII组在血糖达标时间、胰岛素用量、全身并发症之间相比较差异亦有显著性(P<0.01)。 结论：对于围手术期的糖尿病患者,胰岛素泵的临床应用优于常规的胰岛素注射方式。胰岛素泵治疗是糖尿病患者围手术期符合生理机能的一种快捷、安全、有效的治疗方法。

AIM:To observe the value of clinical application of continuous subcutaneous insulin infusion(CSII) with the insulin pump in diabetic patients before and after surgery. METHODS: Fifty diabetic patients (50 eyes) needed to treat with vitrectomy were randomized.27 cases were treated with insulin pump of CSII and 23 cases were treated with daily multi-subcutaneous insulin injection( MSII). The dosage was adjusted according to the blood glucose test results. The differences with the two treatments in blood glucose control level and the time when blood glucose was controlled were compared. RESULTS: Before and after surgical treatment, the two methods were effective in controlling blood sugar to normal or basically normal level, the differences were significant (P<0.05);But the two treatment groups, in the time of blood glucose down to normal, insulin dose and systemic complications,also had significant differences (P<0.01). CONCLUSION: For perioperative diabetes, the clinical application of insulin pump treatment method is better than that of the conventional way of insulin injection.It is a fast, safe and effective treatment method fit for humans physiological function.