目的：探讨不同方法治疗新生儿泪囊炎的临床疗效。 方法：对2010-07/2011-12在我院门诊就诊的386例412眼新生儿泪囊炎患儿先后采用泪囊按摩法、泪道冲洗法、泪道探通联合泪道内注药法治疗，观察3种疗法的效果，对组间结果进行统计分析。 结果：患者412眼中泪囊按摩法治愈97眼，治愈率为23.5%；泪道加压冲洗法治愈98眼，治愈率为31.1%，与泪囊按摩法比较，差异有统计学意义（P＜0.05）；泪道探通联合注药法治愈213眼，治愈率为98.2%，与泪囊按摩法、泪道冲洗法比较，差异有显著统计学意义（P＜0.01）。 结论：眼部泪囊区按摩治疗新生儿泪囊炎简单、易行，适合于早期治疗；对按摩无效的患儿可采用泪道加压冲洗和泪道探通术；采用泪道探通联合泪道内注入典必殊眼膏能明显提高新生儿泪囊炎的治愈率，可作为一种有效的治疗方法。

AIM：To explore the clinical efficacy of different approaches to the treatment of neonatal dacryocystitis.  METHODS：Totally 386 cases (412 eyes) of neonatal dacryocystitis in outpatient service of our hospital from July 2010 to December 2011 were treated with lacrimal sac massage, irrigation of lacrimal passage and probing combined with drug injection of lacrimal passage to observe the effect of three kinds of therapy and the results were statistically analysed between groups.  RESULTS：Of 412 eyes, lacrimal sac massage cured 97 eyes, the cure rate was 23.5%; lacrimal passage pressure washing cured 98 eyes, the cure rate was 31.1%.Compared with lacrimal sac massage, the difference was statistically significant (P<0.05); Probing combined with drug injection of lacrimal passage cured 213 eyes , the cure rate was 98.2%.Compared with lacrimal sac massage and irrigation of lacrimal passage, the difference was statistically significant (P<0.01). CONCLUSION：Eye lacrimal sac massage therapy in neonatal dacryocystitis is simple, easy, suitable for early treatment; Pressure washing and probing of lacrimal passage can be used in invalid children; Probing combined with tobradex eye ointment injection of lacrimal passage can significantly improve the cure rate of neonatal dacryocystitis ,which can be used as an effective treatment method.

Social Development Plan of Yunnan Provincial Science and Technology Department (2009CA008)