目的：探讨圆锥角膜患者角膜地形图的特点，为圆锥角膜的诊断提供客观可行的依据。利用角膜地形图对角膜屈光手术前患者进行严格筛选，提高手术的预测性。 方法：圆锥角膜患者11眼，疑似圆锥角膜患者11眼，使用SIRIUS 3D角膜地形图仪进行检查，获取角膜前后表面地形图形态、角膜中央屈光力、 角膜中央下方与上方平均屈光力之差(I-S)、表面非对称指数(SAI)。 结果：圆锥角膜患者角膜最薄点多不在角膜中央，多位于第三象限圆锥的顶部，与屈光力逐渐降低的同心圆包绕。圆锥角膜患者与疑似圆锥角膜患者之间的角膜中央屈光力差异有统计学意义。圆锥角膜、疑似圆锥角膜患者角膜厚度的差异有明显的统计学差异。SIRIUS 3D角膜地形图中圆锥角膜患者及疑似圆锥角膜患者角膜前后表面最高点、及角膜最薄点三者基本吻合，符合圆锥角膜的发展趋势。其矢量图在圆锥角膜的判定中有一定的意义。 结论:SIRIUS 3D角膜地形图是早期诊断圆锥角膜的有效方法，为角膜屈光术前患者的筛查提供可靠依据。

AIM:To discuss the characteristics of corneal topography for keratoconus patients and provide objective and feasible basis for diagnosis of keratoconus. And to conduct strict screening on corneal refractive surgery patients using corneal topography to increase the predictability of the operation. METHODS:Eleven cases of keratoconus patients and 11 eyes of suspected keratoconus patients used the SIRIUS 3D corneal topography instrument to check. The morphology of corneal anterior and posterior surface topography, central corneal refractive power, inferior and superior central corneal difference of average refractive power (I-S) and surface asymmetric index (SAI)were obtained. RESULTS: Keratoconus corneal thinnest point was not in the central cornea,but located to the top of the cone of the third quadrant, and surrounded by the concentric circles with refractive power gradually reduced.The difference in central corneal refractive power between keratoconus and suspected keratoconus had statistical significance. Keratoconus and suspected keratoconus corneal thickness difference was statistically significant difference.The highest points on corneal anterior and posterior surface and corneal thinnest point of keratoconus and suspected keratoconus were generally identical in SIRIUS 3D corneal topography, which accorded with the trend of the development of keratoconus. Its vectogram has a certain significance in the judgement of keratoconus. CONCLUSION: The SIRIUS 3D corneal topography is an effective method of early diagnosis of keratoconus, providing a reliable basis for the patients screening before corneal refractive surgery.