目的：对湖北地区20～29岁人群的角膜散光情况与不同近视度数的关系进行调查，找出其变化规律。 方法：用角膜地形图对随机抽取的2254例湖北地区20～29岁青年居民进行散光度、轴向及近视度数的测定，并分析其变化规律。 结果：湖北地区20～29岁居民中，各个近视度段散光在26°～150°范围内所占人数比例最大，各个近视度段均呈现顺规散光人数多于逆规散光。其中女性高度近视段约为75.3%，中度近视段约为82.7%，低度近视段约为87.2%；男性高度近视段约为74.6%，中度近视段约为83.0%，低度近视段约为82.3%。20～29岁男性高度近视段顺规散光人数比例高于其他两组；女性低度近视段顺规散光人数比例低于其他两组，差异有统计学意义。20～29岁人群中女性中度近视段顺规散光人数比例高于同近视度男性组，且女性总体组顺规散光人数比例高于男性总体组，差异有统计学意义。20～29岁男、女性高度近视组200°以内散光人数比例均低于中度近视组，差异有统计学意义。 结论：湖北地区20～29岁居民中，各个近视度段散光在26°～150°范围内所占人数比例最大，且各个近视度段不论男女均呈现顺规散光人数多于逆规散光；男性高度近视段顺规散光人数比例高于其他两组，女性低度近视段顺规散光人数比例低于其他两组；女性中度近视段顺规散光人数比例高于同近视度男性组，且女性总体组顺规散光人数比例高于男性总体组；男、女性高度近视组200°以内散光人数比例均低于中度近视组。

AIM:To investigate the relationship between the corneal astigmatism and different myopic diopters in 20-29 years-old people in Hubei Province so as to find out the change rule. METHODS:A random sample of 2254 cases of 20-29 years old youth residents in Hubei Province were chosen and the astigmatic diopter, axis and myopic diopter with corneal topography were determined to analyse the change rule. RESULTS: In the 20-29 year-old residents with myopia and astigmatism in Hubei Province, astigmatism with the rule in the three sections of high,moderate,and low myopia were 79.48%, 68.95% and 69.48%, astigmatism against the rule were 20.52%, 31.05% and 30.52% respectively for men; astigmatism with the rule in the three sections of myopia were 80.22%, 75.28%, and 66.92%, astigmatism against the rule were 19.78%, 24.72% and 30.08% respectively for women, indicating a higher proportion of astigmatism with the rule than astigmatism against the rule; the proportion of astigmatism was high in the range of 26 ° -150 °, which were approximately 74.6%, 83.0% and 82.3% respectively in the three sections of myopia for men, showing the proportion in the moderate myopia section the highest, and which were approximately 75.3%, 82.7% and 87.2% respectively in the three sections of myopia for women showing the proportion in the low myopia section the highest ;visible at the same time, the proportion of astigmatism with the rule in the mens moderate myopia section was higher than that in the women’s the same section, while that in the women’s high and low myopia sections was higher than that in the men’s same sections. CONCLUSION: In the 20-29 year-old residents with myopia and astigmatism in Hubei Province, astigmatism occurred in a high proportion within the range of 26 ° to 150 °; the proportion of astigmatism with the rule was higher than that of astigmatism against the rule; the proportion of astigmatism with the rule of women was higher than that of men in the high and low myopia sections,while the proportion of astigmatism with the rule of men was higher than that of women in the moderate myopia section. The differences were statistically significant.