目的：探讨可调节人工晶状体植入术后远期视力、表观调节力及视觉症状等情况。方法：病例对照研究。选择43例49眼拟行白内障超声乳化摘除联合囊袋内人工晶状体植入术的白内障患者,其中21例25眼植入Tetraflex可调节人工晶状体（Tetraflex组）,22例24眼植入Acrysof SA60AT单焦点人工晶状体（SA60AT组）,对比研究两组患者术后3,6,24mo裸眼远视力、最佳矫正远视力、裸眼近视力、最佳矫正远视力下近视力、等效球镜度、表观调节力、脱镜率以及患者满意度情况。采用SPSS 13.0统计软件包进行统计学处理。结果：术后随访期间,两组患者的裸眼远视力和最佳矫正远视力差异无统计学意义(P>0.05)；Tetraflex组患者的裸眼近视力和最佳矫正远视力下近视力与单焦组比较差异有统计学意义(P<0.05)。术后应用负镜片法测得的表观调节力：术后3mo,Tetraflex组为3.56±1.20D,SA60AT组为-0.25±0.20D；术后6mo, Tetraflex组为3.08±1.30D, SA60AT组为-0.20±0.18D；术后24mo, Tetraflex组为285±1.22D, SA60AT组为-0.15±0.16D,差异均有统计学意义(P<0.05)。近距离阅读时戴老视镜情况和对疗效的满意度情况,Tetraflex可调节人工晶状体组均明显优于单焦组,差异有统计学意义(P<0.05)。结论：与传统的单焦点人工晶状体相比,Tetraflex可调节人工晶状体满足了患者视远、视近的要求,并可提供较好的表观调节力,虽远期有下降趋势,但逐渐平稳。

AIM: To evaluate long-term visual performance after Tetraflex accommodative intraocular lens(AIOL) implantation by measuring the visual acuity, pseudophakic accommodation, visual symptoms.METHODS: Case-control study. Forty-three consecutive age-related cataract patients (49 eyes) were enrolled and received routine cataract phacoemulsification with IOL implantation surgery. All the cases were randomly divided into 2 groups: Tetraflex group(21 cases 25 eyes), which received Tetraflex AIOL ( and SA60AT group(22 cases 24 eyes), which received Acrysof SA60AT IOL (3, 6, and 24 months postoperatively, the uncorrected and best-corrected distance visual acuity(UCDVA and BCDVA), uncorrected and best distance-corrected near visual acuity(UCNVA and BCNVA), pseudophakic accommodation, diopter and complications were studied between the two groups. Questionnaire of visual function was used to investigate the visual symptoms. The indexes were analyzed by SPSS13.0 statistics software.RESULTS: There were no statistically significant differences in UCDVA and BCDVA between the two groups 3, 6, and 24 months postoperatively (P>0.05); while there were statistically significant differences in UCNVA and BCNVA (P<0.05 ). Minus lens method was applied to evaluate the pseudophakic accommodation: after 3 months, Tetraflex group was 3.56±1.20D, SA60AT group was -0.25±0.20D; after 6 months, Tetraflex group 3.08±1.30D, SA60AT group -0.20±0.18D; 24 months later, Tetraflex group 2.85±1.22D, SA60AT group -0.15±0.16D. Tetraflex AIOL lens provided excellent pseudophakic accommodation than monofocal IOL(P<0.05), and also in close reading and satisfaction of the curative effects (P<005). CONCLUSION: Compared with monofocal IOL, Tetraflex AIOL provides age-related cataract patients with good distance and near vision, as well as pseudophakic accommodation. Although pseudophakic accommodation of Tetraflex AIOL decreases in long-term, it gradually becomes stable.