目的：探讨高度近视眼的眼轴(AL) 、屈光度(D)、角膜曲率及角膜厚度(CCT)的相互关系。方法：将高度近视患者80例158 眼分为3组：A 组为高度近视(-6.00～-9.00D)26例46眼,B组为超高度近视(-9.25～-20.00D) 57例97眼,C 组为超高度近视(≥20.25D)9例15眼, 分别测量3组患者眼轴(AL)、屈光度(D)、角膜曲率(K₁,K₂) 值及角膜厚度(CCT)。结果：AL值：A 组26.75±0.15mm,B组29.25±0.19mm,C组32.27±0.84mm,三组比较差异均有统计学意义(均P<0.05)；A,B,C组屈光度与AL呈正相关(r=0.352,0.715,0.622；P<0.05),三组意义不同,分别为低、高、高相关；A,B,C组AL与角膜曲率均呈负相关(r₁=-0.630,-0.494,-0.750；r₂=-0.609,-0.465,-0.782；P<0.05),眼轴越长曲率越低；A组屈光度与角膜曲率(K₁,K₂)值呈正相关(r₁=0.575,r₂=0.346,P<0.05),B和C组不相关；A,B和C 组角膜厚度与角膜屈光力无相关性。结论：眼轴增长是高度近视发病的主要影响因素,角膜曲率改变是次要因素,而与角膜厚度不相关。

AIM:To study the correlation of the axial length(AL), diopter(D), keratometric power (K₁,K₂) and central corneal thickness(CCT) of high myopia.METHODS :Eighty cases(158 eyes ) were divided into 3 groups depending on their diopters: 26 cases(46 eyes) with diopters arranged from -6.00D--9.00D in group A (myopia group); 57 cases(97 eyes) with diopters arranged from -9.25D--20.00D in group B (high myopia group); 9 cases(15 eyes) with diopters over 20.25D in group C (super high myopia group). AL, diopter, keratometric power and CCT of three groups were measured. RESULTS: There were significant difference(P<0.05) among AL values of three groups (group A: 26.75±015mm; group B: 29.25±0.19 mm; group C: 32.27±0.84mm). Positive correlations existed between AL values and diopters of three groups （r=0.352,0.715,0.622;P<0.05）,while negative correlations between AL values and K₁、K ₂（r₁=-0.630,-0.494,-0.750, r₂=-0.609,-0.465,-0.782;P<0.05）. Positive correlations existed between diopters and K₁,K₂ in group A, while did not exist in group B and C. No correlation existed between CCT and diopters of three groups.CONCLUSION: Axial growth was the main influence factor of high myopia, keratometric power was the second factor, and CCT has no influence.

国家自然科学基金(No. 81170826)