目的：评估玻璃体切割联合内界膜剥离治疗视网膜静脉阻塞（retinal vein occlusion, RVO）继发黄斑水肿的治疗效果。 方法：对12例视网膜中央或分支静脉阻塞的患者行玻璃体切割联合内界膜剥离,记录术前术后最佳矫正视力（BCVA）及黄斑中心凹厚度。结果：术前平均黄斑中心凹厚度563.9±90.0μm, 术后2mo黄斑中心凹的平均厚度为361±61.1μm,术后黄斑厚度较术前明显降低（P=0.001）。所有CRVO的BCVA均有所提高,而8例BCVO只有4例术后视力得到提高。术前平均标准对数视力表的BCVA为1.23±0.29,术后为1.06±0.49,术后与术前相比无统计学意义（P=0.09）。结论：玻璃体切割联合内界膜剥离可显著改善RVO继发的黄斑水肿,但术后视力提高不明显。

AIM:To evaluate the effects ofpars plana vitrectomy(PPV) combined with internal limiting membrane peeling for the treatment of macular edema secondary to retinal vein occlusion (RVO).METHODS:Twelve cases of visual loss due to macular edema caused by central RVO or branch RVO underwentPPV combined with internal limiting membrane peeling. Best-corrected visual acuity (BCVA) and central foveal thickness by optical coherence tomography(OCT) were measured pre- and postoperatively then compared to assess the outcome of surgery.RESULTS:In all cases retinalthickeness diminished within 2 months of surgery. Visual acuity improved in all of the central RVO cases and 4 out of 8 branch RVO cases. The decrease in macular thickness was statistically significant (mean postoperative macular thickness 361±61.1μm versus mean preoperative macular thickness 563.9±90.0μm, P=0.001, t-test). The improvement in BCVA was not statistically significant (mean preoperative BCVA in LogMAR 1.23±0.29 versus mean postoperative BCVA in LogMAR 1.06±0.49, P=0.09, t-test).CONCLUSION: In eyes with macular edema secondary to RVO,PPV combined with internal limiting membrane peeling can resolve macular edema, but the improvement in BCVA was not statistically significant in this study.