方法：对2011-06/07间来本院就诊的158例近视患者，其中男66例，女92例，平均屈光度-4.46±1.31D，平均年龄15.22±0.96岁。在进行散瞳和医学验光的基础上配戴矫正眼镜，试验组72例，对照组86例。试验组使用七叶洋地黄双苷滴眼液3次/d，滴双眼，30d为1疗程。2wk复查1次，对调节幅度、调节滞后、调节灵敏度、正负相对调节和屈光度进行评价，所得数据采用单因素方差分析。

结果：试验组调节灵敏度改善较对照组明显，差异有统计学意义(左眼：F=6.342，P<0.05； 右眼：F=7.966， P<0.05； 双眼F=6.922，P<0.05)。负相对调节治疗组改善较对照组明显，差异有统计学意义(F=6.102，P<0.05)。屈光度变化两组对比无统计学意义(F=2.361，P>0.05)。

结论：七叶洋地黄双苷滴眼液能有效改善青少年近视眼的调节功能。

METHODS: Totally 158 cases of myopia with an average age of 15.22±0.96 years old were selected between June 2011 and July 2011, including 66 males and 92 females, with mean refractive diopter -4.46±1.31D. Based on pupil dilation and medical optometry, the patients wore corrective glasses, and then they were divided into experimental group 72 patients, and control group 86 patients. The experimental group was used Esculin and Digitalisglycosides Eye drops 3 times a day for both eyes, 30 days a course, and reviewed every two weeks to evaluate the amplitude of accommodation, accommodative lag, accommodative sensitivity, positive and negative relative accommodation, and the data obtained were analyzed using ANOVA.

RESULTS: Theaccommodative sensitivity in the experimental group was obviously improved compared with that in control group, and the difference was statistically significant(left eye:F=6.342,P<0.05; right eye: F=7.966, P<0.05; both eyes: F=6.922,P<0.05). The negative relative accommodation in the experimental group was obviously improved compared with that in control group, and the difference was statistically significant(F=6.102,P<0.05). There was no significant difference in refractive diopter between the two groups(F=2.361,P>0.05).

CONCLUSION: Esculin and Digitalisglycosides Eye drops can effectively improve the accommodation function of juvenile myopia.