[关键词]
[摘要]
目的:观察复方樟柳碱注射液治疗前部缺血性视神经病变(ischemic optic neuropathy,ION)的临床疗效。
方法:选择2011-12/2012-06于我院就诊的前部ION患者82例为研究对象,全部为单眼病变,按照随机数字表法随机将其分为两组,观察组42例,对照组40例,对照组给予患者复方丹参注射液静脉滴注,观察组在对照组患者治疗的基础上再给予2mL复方樟柳碱注射液局部皮下注射治疗,注射部位为患侧眼颞浅动脉旁。观察两组疗效。
结果:观察组治疗2个疗程后总有效率为88.1%,显著高于对照组,经χ2检验,P<0.05,差异明显; 并发症发生率为2.4%,与对照组比较差异不明显,经χ2检验,P>0.05。
结论:复方樟柳碱注射液治疗前部ION有着明显的临床效果,与传统方法合用并未使不良反应发生率增加,具有安全、简单、易行的特点。
[Key word]
[Abstract]
AIM: To observe the clinical effect of compound anisodine injection for the treatment of anterior ischemic optic neuropathy(ION).
METHODS: From December 2011 to June 2012, 82 patients with anterior ION were selected as objects in our hospital, they were all ill in single eye. They were randomly divided into observation group and control group. Observation group(compound anisodine injection group, n=42)and control group(salvia hormone injection group, n=40). We observed the curative effects.
RESULTS: In observation group, the total effective rate was 88.1% after 2 courses of treatment, it was significantly higher than the control group, after χ2 test, P<0.05. The complication rate was 2.4%, the differences were not apparent when compared with the control group, after the χ2 test, P>0.05.
CONCLUSION: The clinical effect of compound anisodine injection for the treatment of anterior ION was obvious, it does not increase the incidence of adverse reactions when combined with traditional methods, it has the characteristics of safety, simple, and easy to practice.
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