[关键词]
[摘要]
目的：探讨手机辐射对体外培养大鼠晶状体上皮细胞中Bax表达的影响。
方法：采用ELISA和免疫组织化学法检测手机辐射后在MEM培养液培养28d晶状体中Bax的表达水平，裂隙灯下观察晶状体的混浊程度。
结果：手机辐射组Bax的表达量均显著高于对照组(P<0.05)，Bax的表达量随着手机辐射时间的增加而增加，且手机辐射组的晶状体混浊程度较对照组明显增加。
结论：手机微波辐射可增加体外大鼠晶状体中Bax的表达， 导致晶状体上皮细胞凋亡和白内障的发生。
[Key word]
[Abstract]
AIM: To study the effect of mobile microwave on the expression of Bax in the lens epithelial cells of rat
in vitro.
METHODS: Bax expression was detected by ELISA and immunohistochemistry after the lenses of rats were cultivated in MEM culture medium.
RESULTS: The expression of Bax in the mobile microwave groups was significantly higher than the control group(P<0.05)and the expression of Bax accumulated while it was exposed in the mobile microwave.
CONCLUSION: Mobile microwave can induce the expression of Bax in the lens epithelial cells of rat and cause cataract.
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