方法：选择2011-01/12我院眼科诊治的白内障患者75例78眼，分为两组，A组为单纯性年龄相关性白内障患者35例38眼，B组为糖尿病合并白内障患者40例40眼。观察分析术前、术后1d； 1wk； 1，3mo时两组患者的主观感觉、泪膜破裂时间(tear break-up time， BUT )、基础泪液分泌试验(SchimerⅠ test， SⅠt)、角膜上皮荧光素染色(corneal fluorescein staining，FL)、泪河宽度检查等情况。

结果：术前两组相比各项检查结果无统计学差异(P>0.05)； A组术后1d，1wk时干燥、异物感加重，术眼BUT明显缩短，与术前相比差异具有统计学意义(P<0.05)； 术后1，3mo接近术前水平，差异无统计学意义(P>0.05)。B组术后1d，1wk，1mo时干燥、异物感加重，术眼BUT明显缩短，与术前相比差异有统计学意义(P<0.05)； 术后3mo接近术前水平，差异无统计学意义(P>0.05)。在术后各时间点，B组患者干燥、异物感症状明显重于A组患者，角膜荧光素着色点明显多于A组，差异均有统计学意义(P<0.05)。

结论：糖尿病合并白内障患者行小切口晶状体囊外摘出联合IOL植入术后早期会出现泪膜稳定性下降，相对于单纯性年龄相关性白内障患者，症状更明显，持续时间更长，但是随时间推移，患者不适症状可逐渐缓解。

METHODS:Seventy-five patients(78 eyes)who received small incision extracapsular cataract extraction in our hospital from January to December 2011 were divided into two groups: 35 patients(38 eyes)with age-related cataract in group A and 40 patients(40 eyes)with both diabetes and cataract in group B. The subjective complains of dry eye, tear break-up time, corneal fluorescein staining, Schirmer I test and the height of tear meniscus were measured preoperatively and 1 day, 1 week, 1 month and 3 months postoperatively respectively.

RESULTS:There was no significant difference between the two groups preoperatively(P>0.05). Compared with data before operation, the group A's subjective complains of dry eye increased and the mean tear break-up time reduced greatly at 1 day, 1 week postoperatively(P<0.05). They returned to their preoperative levels at 1 month and 3 month postoperatively(P>0.05). Compared with data before operation, the group B's subjective complains of dry eye increased and the mean tear break-up time reduced greatly at 1 day, 1 week and 1 month postoperatively(P<0.05). They returned to their preoperative levels at 3 month postoperatively(P>0.05). In the different time points after operation, the degree of subjective complains of dry eye were significantly more severe in group B than in group A, and the corneal fluorescein staining scores were significantly higher in group B than in group A(P<0.05).

CONCLUSION:The tear film stability of patients with both diabetes and cataract reduced in early stage after small incision extracapsular cataract extraction and intraocular implantation. Compared with patients with age-related cataract, patients with both diabetes and cataract recovered much more slowly. The subjective complains of dry eye were more obvious in patients with both diabetes and cataract, but they would disappear with the passage of time.