方法：采用病例对照研究的方法比较两种术式治疗大角度外斜视的效果。将39例伴有弱视的大角度外斜视患者按术式分为A组和B组，A组做单眼常规量外直肌后退加外直肌错位缘切并内直肌缩短术； B组行单眼常规外直肌后退内直肌缩短术。A，B组按1：2配比，两组的病例在年龄和视力方面相匹配。治愈标准：术后6mo之后的眼位≤±8^△为治愈。用四格表Fisher确切概率检验法比较两组的治愈率。

结果：A组的治愈率为84.6%，B组的治愈率为46.2%，两组间的治愈率经统计学分析有显著性意义(P<0.05)。

结论：单眼外直肌常规量后退加外直肌错位缘切并内直肌缩短术治疗大角度外斜视比传统方法安全、有效。

METHODS: A case-control study was used to compare two operation treatments of large angleexotropia. Totally 39 patients of large angle exotropia complied with highly amblyopic were divided into group A and group B according to the surgeon methods. Monocular normal quantity of lateral rectus recession combined the edge cutting in the external rectus and medial rectus shortening were performed in group A. The same operations except the edge cutting in the lateral rectus were performed in group B. A: B was equal to 1:2, with age and visual acuity matched. The eye position ≤±8^△ 6 months postoperative was seen as the criteria of cure. The cure rate of two groups were compared with χ²- Fisher's exact probability test.

RESULTS: The cure rate was 84.6% in group A and 46.2% in group B. There was significant difference in the cure rate between the two groups(P<0.05).

CONCLUSION: The operation that the monocular normal quantity of lateralrectus back combined the edge cutting in the external rectus is safe and effective than the traditional method.