方法：检索PubMed 数据库2000-01/2012-08有关TON的文献，对年代、作者、语种、国家等进行统计分析，采用共词聚类分析方法构造高频主题词共现矩阵，并进行聚类分析，通过分析不同类别主题词相关的文献，得出目前TON的研究热点。

结果：共检出 TON相关文献785篇，美国、英国、中国产文量最高，数量上英语文献占绝对优势。统计出高频主题词50个，聚类分析显示高频主题词主要聚类于10个类别。作者中，以Levkovitch-Verbin H发文量最大，来源期刊中，以《Investigative Ophthalmology & Visual Science》载文量最多。共提取出主题词1 383个，得出出现频率>12次的高频主题词32个。聚类分析显示近期TON研究热点在于：(1)TON的手术治疗研究；(2)视神经损伤的病理生理学研究；(3)TON的病理学及诊断研究；(4)TON动物模型及药物治疗研究；(5)TON流行病学研究。

结论：近期TON文献增长不快，美国、英国是TON研究大国。国内外TON的研究热点主要集中在TON的手术治疗、诊断、病理和药物治疗等5个方向，我们的研究结果为国内相关科研和临床工作者提供了重要参考信息。

METHODS: Candidate publications from January 2000 to August 2012 were collected by searching PubMed with the MeSH word ‘traumatic optic neuropathy' and without language restriction. Bibliometric techniques used in this study included a statistical analysis of publication counts by authors, countries and journals and a co-word cluster analysis of highly-frequent MeSH/subheadings words.

RESULTS: Totally 785 articles about TON were indexed in PubMed. The United States, the United Kingdom and China were the largest three producers about TON. English was the top language. Levkovitch-Verbin H published 9 papers and ranked the top, followed by Lorber B. Investigative Ophthalmology & Visual Science published 52 papers and ranked the top. 32 highly-frequent MeSH/subheadings words for more than 12 times occurrences in the papers about TON were extracted for cluster analysis. These words were classified into 6 aspects:(1)Surgery therapy for TON;(2)Physiopathology of optic nerve injury;(3)Pathological appearance and diagnosis of TON;(4)Animal model and drug therapy for TON;(5)Etiology of TON.

CONCLUSION: Slow growth has occurred in the research field of TON. The United States and the United Kingdom are the top 2 countries in this field. The international main research focus included 5 aspects. This study results provide important reference for domestic scholars in TON correlated scientific study and clinic therapy.