方法：选择行有晶状体眼人工晶状体(implantable collamer lens，ICL)植入术的高度近视眼患者25例50眼，用尼德克波前像差仪测量患者6mm瞳孔区域内术前和术后1mo的波前像差值，对其进行配对t检验。

结果：ICL植入眼术后1mo全眼总体波前像差(OPD Total)、眼内总体波前像差(Internal Total)较术前明显下降(P<0.05)。全眼总体高阶波前像差(OPD High)、全眼总体球面像差(OPD T.SPH)、全眼总体彗差(OPD T.Coma)、全眼总体三叶草(OPD T.Trefoil)、眼内总体彗差(Internal T.Coma)较术前有不同程度升高，具有统计学意义(P<0.05)。角膜总体波前像差(C-Total)、角膜总体高阶波前像差(C-High)、角膜球差(C-T.Sph)、角膜彗差(C-T.Coma)、角膜四叶草(C-T.4Foil)较术前有不同程度升高，角膜三叶草(C-T.Trefoil)较术前明显下降，但差异均无统计学意义。

结论：有晶状体眼后房型人工晶状体植入术虽然显著降低了高度近视眼的总体波前像差，但术眼球面像差、彗差、三叶草等高阶波前像差有不同程度增加。

METHODS: Wave-front aberrations were evaluated by NIDEK Optical path differences(OPD)in 50 eyes of 25 high myopia patients who received ICL implantation preoperatively and 1 month postoperatively. The results were analyzed by Student's t test.

RESULTS:The Zernike functional values of total aberration and internal total aberration in 6mm pupil size area of the postoperative eyes implanted with ICL were found significantly statistical lower(P<0.05)than those of the preoperative eyes. The Zernike functional values of total high-order aberration, total spherical-like aberration, total coma-like aberration, total trefoil-like aberration and internal total coma-like aberration were found significantly statistical higher(P<0.05)than those of the preoperative eyes. The Zernike functional values of cornea aberration were not found significantly statistical changes compared with those of the preoperative eyes.

CONCLUSION: Although total aberrations could be decreased by implantable collamer lens implantation in high myopia eyes, high-order aberrations such as total spherical-like aberrations, total coma-like aberrations and total trefoil-like aberrations are increased in certain degree.