[关键词]
[摘要]
目的：应用光学相干断层扫描(optical coherence tomography，OCT)观测分析视网膜分支静脉阻塞(branch retinal vein occlusion，BRVO)致黄斑水肿(macular edema，ME)患者行氩激光光凝后视网膜水肿变化。
方法：BRVO致视网膜水肿行氩(绿)激光光凝术，格栅状光凝12眼，光凝前及光凝后1，2，3，6mo分别行OCT图像检查。应用CIRRUS OCT自带程序行黄斑ETDRS区视网膜厚度分析，以中心凹1mm区域厚度及其变化值作统计学分析。
结果：记录光凝后1，2，3，6mo黄斑中心1mm区厚度变化平均值分别为+7.3μm，-48.5μm，-79.0μm，-101.9μm。统计学分析视网膜厚度光凝前与光凝后2mo后两组间差异有统计学意义(P<0.05)，光凝前与光凝后1mo差异无统计学意义。
结论：OCT检测能准确定量定性测算黄斑区视网膜厚度变化，可观察氩激光光凝治疗BRVO致 ME疗效，可作为光凝治疗疗效判断指标。
[Key word]
[Abstract]
AIM: To analyze the effect of argon laser photocoagulation in the treatment of macular edema related to branch retinal vein occlusion(BRVO)with optical coherence tomography(OCT).
METHODS: Consecutive retrospective analysis of visual acuity(VA)and OCT from eyes treated with grid macular photocoagulation for BRVO-related macular edema were performed. Examed VA and central retinal thickness(CRT)before and after treating 1 month, 2, 3 and 6 months respectively were examined. Analysis of variance was used to compare pre- and post-treatment VA and CRT.
RESULTS: The macular retinal thickness was 352.3μm before photocoagulation. Within 6 months from symptom onset, 12 eyes had better visual acuity and less CRT than before photocoagulation.
CONCLUSION: OCT is able to quantify the development and resolution of macular edema secondary to BRVO. It is a useful and non-injury tool to analyze the effect of photocoagulation.
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